Drug intelligence / Profile preview

thiamine + pyridoxine + cyanocobalamin (Grand Medical Group AG)

Development stage
Unknown
Lead developer
Grand Medical Group
Modality
Small Molecules
Administration
Oral
01

Overview

Enfin-Forte is a high-dose neurotropic vitamin complex containing thiamine (Vitamin B1), pyridoxine (Vitamin B6), and cyanocobalamin (Vitamin B12). Developed by Grand Medical Group, it is primarily indicated for the treatment of various neurological disorders, including neuralgia, neuritis, radicular syndrome, and polyneuropathy (such as diabetic or alcoholic neuropathy). The combination of these B-complex vitamins acts synergistically to support the metabolism of the central and peripheral nervous systems. Thiamine serves as a cofactor for enzymes involved in carbohydrate metabolism and nerve impulse conduction; pyridoxine is essential for the synthesis of neurotransmitters like dopamine, serotonin, and GABA; and cyanocobalamin is crucial for myelin sheath formation and nucleic acid synthesis. The "Forte" designation typically refers to the oral tablet formulation, which is often used for maintenance therapy following acute treatment with injectable forms.

Brand names
Enfin-Forte
Other names
Vitamin B1 + Vitamin B6 + Vitamin B12
02

Targets

DDC (Aromatic L-amino acid decarboxylase)MTR (Methionine synthase)PDH (Pyruvate dehydrogenase complex)

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