Drug intelligence / Profile preview

tislelizumab + cisplatin + gemcitabine + trilaciclib + FSME-IMMUN

Development stage
Unknown
Lead developer
BeiGene
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules, Vaccines & Immunotherapeutics
Administration
Intramuscular, Intravenous
01

Overview

The entity "tislelizumab + cisplatin + gemcitabine + trilaciclib-Pfizer-tick-borne encephalitis" appears to be an erroneous concatenation of two distinct therapeutic categories: a cancer treatment regimen and a viral vaccine. The first part of the name describes a combination of **tislelizumab** (a PD-1 blocking monoclonal antibody), **cisplatin** and **gemcitabine** (cytotoxic chemotherapies), and **trilaciclib** (a CDK4/6 inhibitor used to reduce chemotherapy-induced myelosuppression). This regimen is typically investigated for advanced solid tumors such as small cell lung cancer or urothelial carcinoma. The second part, "Pfizer-tick-borne encephalitis," refers to **FSME-IMMUN** (marketed as TicoVac in the US), an inactivated whole-virus vaccine developed for the prevention of tick-borne encephalitis (TBE). FSME-IMMUN is produced from the Neudörfl strain of the TBE virus and is administered intramuscularly to induce neutralizing antibodies. There is no known clinical use, trial, or biological rationale for a single combination product containing all five of these agents; the name likely resulted from a data processing error where a cancer regimen was appended to a vaccine entry.

Brand names
FSME-IMMUNTicoVacCosela
Other names
Tick-Borne Encephalitis Vaccine (Inactivated)TBE Vaccine
02

Targets

PDCD1 (Programmed cell death protein 1 receptor)CDK6 (Cyclin-dependent kinase 6)E (Tick-borne encephalitis virus envelope protein)CDK4 (Cyclin-dependent kinase 4)DNAFcγR (Low affinity immunoglobulin gamma Fc region receptor II-c)

Beyond the preview

Go deeper on tislelizumab + cisplatin + gemcitabine + trilaciclib + FSME-IMMUN.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on tislelizumab + cisplatin + gemcitabine + trilaciclib + FSME-IMMUN.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call