Drug intelligence / Profile preview

TJ-15 + TJ-17

Development stage
Unknown
Lead developer
Tsumura
Administration
Oral
01

Overview

TJ-15 + TJ-17 is a combination of two traditional Japanese Kampo herbal formulas, Hwang-Yeon-Hae-Dok-San (TJ-15) and Ou-Ryung-San (TJ-17). This combination has been studied for the treatment of atopic dermatitis, particularly in patients with the Dampness-Heat pattern as defined by traditional East Asian medicine. The mechanism of action is not fully elucidated but is believed to involve anti-inflammatory and immunomodulatory effects due to the complex mixture of herbal ingredients present in both formulas. In clinical studies, this combination has shown efficacy in reducing symptoms and severity indices associated with atopic dermatitis without significant adverse events[1].

Other names
Hwang-Yeon-Hae-Dok-San + Ou-Ryung-San
02

Targets

CYP3A4 (Cytochrome P450 3A4)ABCB1 (P-glycoprotein)

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