tobramycin + dexamethasone (União Química)

Tobracort is an ophthalmic fixed-dose combination drug containing the aminoglycoside antibiotic tobramycin and the synthetic corticosteroid dexamethasone. It is developed by União Química and Azidus Brasil for the treatment of steroid-responsive inflammatory ocular conditions where a bacterial infection or a risk of bacterial ocular infection exists, such as acute bacterial conjunctivitis. Tobramycin provides broad-spectrum antibacterial activity by binding to the 30S ribosomal subunit, thereby inhibiting protein synthesis in susceptible bacteria. Dexamethasone acts as a potent anti-inflammatory agent by binding to glucocorticoid receptors, which leads to the suppression of various inflammatory pathways and the reduction of signs and symptoms like edema and redness.

Brand names

Tobracort

Other names

tobramycin 0.3% + dexamethasone 1%tobramycin + dexamethasone