Drug intelligence / Profile preview

TOM's Superior Sensitivity Relief Toothpaste

Development stage
Unknown
Lead developer
Colgate-Palmolive
Modality
Small Molecules
Administration
Topical
01

Overview

TOM's Superior Sensitivity Relief Toothpaste is a fluoride-free oral care product developed by Colgate-Palmolive under the Tom's of Maine brand. It utilizes Pro-Argin technology, which combines 8% arginine (as arginine bicarbonate) with calcium carbonate. This formulation provides rapid and long-lasting relief from dentin hypersensitivity by physically occluding exposed dentin tubules, thereby sealing the pathways to sensitive tooth nerves. Beyond its use for sensitivity relief, the toothpaste is being investigated for its prebiotic efficacy in modulating the oral microbiome. It promotes the growth of beneficial arginolytic bacteria within dental plaque, which helps neutralize acids and maintain a healthy oral environment, potentially improving overall oral health outcomes.

Brand names
TOM's Superior Sensitivity Relief ToothpasteTom's of Maine Rapid Relief Sensitive
Other names
arginine bicarbonate + calcium carbonate toothpaste

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