torsemide + spironolactone

**Torsemide + spironolactone** is a fixed-dose combination of two diuretics used primarily to manage edema (fluid retention) and hypertension, especially in patients with heart failure, liver cirrhosis, or kidney disorders[1][3][5][7]. Torsemide is a loop diuretic that works by inhibiting sodium reabsorption in the thick ascending limb of the loop of Henle, resulting in increased urine output and reduced fluid overload. Spironolactone is a potassium-sparing diuretic and a mineralocorticoid receptor antagonist, blocking the action of aldosterone and promoting sodium and water excretion while conserving potassium[1][4][6][8]. The combination provides synergistic diuretic effects while mitigating the risk of hypokalemia typically caused by loop diuretics alone. It is indicated for the treatment of edema due to heart failure, liver cirrhosis, chronic kidney disease, and for hypertension when single diuretic therapy is insufficient[1][3][5][7].

Brand names

TEROMIDE PLUS 10TEROMIDE PLUS LS

Other names

spironolactone + torsemide