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TQA3605 + nucleoside analogues
- Development stage
- Unknown
- Lead developer
- Chia Tai-Tianqing Pharmaceutical Group
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
TQA3605 is an orally available small molecule hepatitis B virus (HBV) capsid inhibitor developed by Chia Tai Tianqing Pharmaceutical Group. It is being investigated for the treatment of chronic hepatitis B, particularly in combination with oral nucleoside (acid) analogues (NAs). The drug acts by inhibiting the HBV capsid, thereby interfering with viral replication. Clinical trials are ongoing to evaluate its efficacy and safety both as monotherapy and in combination with NAs in patients with chronic HBV infection, including those who are treatment-naïve or have low viremia[1][2][3].
- Other names
- TQA3605 + NAsTQA3605 + nucleoside (acid) analoguesTQA3605 tablets combined with NAsTQA-3605 tablets combined with NAsTQA 3605 tablets combined with NAs
02
Targets
HBc (Hepatitis B virus core protein)
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