Drug intelligence / Profile preview

triamcinolone acetonide + povidone-iodine + ammonia + lidocaine

Development stage
Unknown
Lead developer
Asclemed USA
Modality
Small Molecules
Administration
Intramuscular, Intraarticular
01

Overview

A multi-component procedural injection kit marketed as **Physician EZ Use Joint Tunnel and Trigger Kit** and associated with Asclemed USA. The kit contains **triamcinolone acetonide** as the principal pharmacologically active therapeutic ingredient, together with **lidocaine** as a local anesthetic, **povidone-iodine** as an antiseptic preparation component, and **ammonia** as an inhalant component. Its therapeutic effect is driven primarily by triamcinolone acetonide, a synthetic glucocorticoid corticosteroid that activates the glucocorticoid receptor to suppress inflammatory gene expression and reduce immune-mediated inflammation; lidocaine contributes local sodium-channel blockade for procedural analgesia. The product is intended for procedural use including intra-articular and intramuscular administration contexts and has been described as an unapproved drug product whose labeling has not been approved by the FDA.

Brand names
Physician EZ Use Joint Tunnel and Trigger Kit
Other names
triamcinolone acetonide + povidone-iodine + ammonia + lidocaine
02

Targets

NaV (Voltage-gated sodium channels)GR (Glucocorticoid receptor)

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