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Trichloroacetic acid (TCA) + glycolic acid (GA) is a chemical peel combination used in dermatology. This combination peel utilizes TCA, an analogue of acetic acid where the three hydrogen atoms of the methyl group have been replaced by chlorine atoms, along with glycolic acid, an alpha hydroxy acid. The combination is used to treat various skin conditions including melasma, lentigines (age spots), signs of aging, and other pigmentation disorders. Clinical studies have shown that using mild concentrations of TCA and glycolic acid together can produce greater improvements for acne and aging skin concerns than either acid alone. The combination works by causing controlled damage to specific skin layers, promoting exfoliation and regeneration of new skin cells.
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