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Tumor neoantigen vaccine (Henan Cancer Hospital)

Development stage
Unknown
Lead developer
Henan Cancer Hospital
Modality
Vaccines & Immunotherapeutics
Administration
Subcutaneous
01

Overview

A personalized therapeutic cancer vaccine developed by Henan Cancer Hospital for the treatment of advanced cancers. The vaccine is designed by identifying patient-specific somatic mutations through genome sequencing to select 'neoantigens'—proteins present only in tumor cells and not in healthy tissue. By customizing the vaccine to each patient's unique tumor profile, it aims to stimulate a robust and highly specific T-cell mediated anti-tumor immune response to eliminate cancer cells that have become resistant to standard therapies.

Other names
Personalized neoantigen vaccineTumor neoantigen vaccine
02

Targets

pMHC (Peptide-MHC complex family)

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