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umbilical cord-derived exosomes (Iffat Anwar Medical Complex)
- Development stage
- Unknown
- Lead developer
- Iffat Anwar Medical Complex
- Modality
- Lipid-based Nanoparticles → Nanoparticles → Drug Delivery Systems
- Administration
- Intravenous
01
Overview
Umbilical cord-derived exosomes are extracellular vesicles harvested from mesenchymal stem cells (MSCs) of the umbilical cord. These vesicles contain a diverse cargo of proteins, lipids, and microRNAs that facilitate intercellular communication and exert potent anti-inflammatory and neuroprotective effects. In the context of Autism Spectrum Disorder (ASD), these exosomes are investigated for their ability to cross the blood-brain barrier and address underlying neurobiological issues such as neuroinflammation and impaired synaptic connectivity. At the Iffat Anwar Medical Complex, this therapy is being evaluated in a randomized controlled trial, often administered intravenously in conjunction with other treatments like photo-biomodulation and autologous platelet-rich plasma (PRP) to potentially improve behavioral outcomes and cognitive function in children with ASD.
- Other names
- Exosome TherapyUC-ExosomesUmbilical Cord Mesenchymal Stem Cell-Derived Exosomes
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