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umbilical cord-derived mesenchymal stem cells (Universitas Diponegoro)

Development stage: Unknown
Lead developer: Diponegoro University
Modality: Stem Cell Therapies → Cell Therapies
Administration: Trans-portal Vein Injection

Overview

This investigational allogeneic cell therapy consists of mesenchymal stem cells derived from umbilical cord tissue (UC-MSCs). Developed by Universitas Diponegoro, it is being evaluated as an adjunctive treatment for infants with biliary atresia undergoing Kasai portoenterostomy. The therapy is administered via intraoperative trans-portal vein injection, with the goal of leveraging the immunomodulatory, anti-inflammatory, and pro-regenerative properties of MSCs to reduce liver fibrosis and improve clinical outcomes, such as liver function and overall survival, in patients with this severe hepatobiliary disease.

Other names: UC-MSCsUmbilical Cord-Derived Mesenchymal Stem CellsUC-MSC therapy for biliary atresia

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