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Umbilical cord mesenchymal stem cells (UCMSCs) are a cell therapy product being investigated by Changhai Hospital for the treatment of post-acute COVID-19 syndrome (Long COVID) and associated chronic cough. UCMSCs are multipotent stem cells known for their significant immunomodulatory, anti-inflammatory, and tissue-regenerative capabilities. In clinical settings, they are typically administered via intravenous infusion to address systemic inflammation and immune dysregulation. Additionally, the hospital is evaluating UCMSC-derived exosomes—small extracellular vesicles secreted by the cells—delivered via nebulized inhalation to specifically target respiratory symptoms like chronic cough. The therapy aims to restore immune homeostasis and facilitate the repair of damaged tissues in patients suffering from persistent post-viral symptoms.
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