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umbilical cord mesenchymal stromal cells + platelet-rich plasma (Liaocheng People's Hospital)

Development stage: Unknown
Lead developer: Liaocheng City People's Hospital
Modality: Cell Therapies
Administration: Intraarticular

Overview

Umbilical cord mesenchymal stromal cells + platelet-rich plasma (Liaocheng People's Hospital) is an experimental combination cell therapy being evaluated for the treatment of knee osteoarthritis. The treatment involves the intra-articular injection of allogeneic mesenchymal stromal cells derived from the umbilical cord (UC-MSCs), suspended in platelet-rich plasma (PRP). UC-MSCs are multipotent cells that exhibit potent anti-inflammatory and immunomodulatory properties, potentially slowing cartilage degradation and promoting a pro-regenerative environment within the joint. PRP acts as a bioactive scaffold and a source of concentrated growth factors (such as TGF-β, PDGF, and VEGF) that enhance the proliferation and chondrogenic differentiation of the MSCs. This synergistic approach aims to alleviate pain and improve joint function in patients with chronic degenerative joint disease.

Other names: UC-MSCs + PRPUmbilical-cord mesenchymal stromal cells (UC-MSCs)

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