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universal influenza vaccine (M2 protein)
- Development stage
- Preclinical
- Lead developer
- Vaxine
- Modality
- Vaccines & Immunotherapeutics, Recombinant Proteins and Enzymes
- Administration
- Intramuscular, Intranasal, Sublingual
01
Overview
The universal influenza vaccine (M2 protein) is a recombinant protein vaccine candidate developed by Vaxine, currently in preclinical stages. It targets the M2 ion channel protein, which is highly conserved across various influenza A virus strains. Unlike traditional vaccines that focus on the highly mutable hemagglutinin protein, this approach aims to induce broad-spectrum immunity that could protect against multiple seasonal and potentially pandemic influenza strains. The vaccine is designed to provide a more durable and cross-reactive immune response, potentially reducing the need for frequent vaccine updates.
- Other names
- M2 protein influenza vaccineM-2 protein influenza vaccineM 2 protein influenza vaccine
02
Targets
M2e (Influenza A matrix protein 2 ectodomain)CHRM2 (M2)
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