Drug intelligence / Profile preview

uridine-2',3'-vanadate

Development stage
Unknown
Modality
Small Molecules
01

Overview

Uridine-2',3'-vanadate is a synthetic small molecule that consists of a uridine nucleoside complexed with vanadium in the form of a vanadate ester. It belongs to the class of organic compounds known as pyrimidones and is structurally related to uridine. The compound has been studied primarily as an experimental tool in biochemical research rather than for therapeutic use. Uridine vanadates are known to act as transition-state analogs for phosphoryl transfer reactions and have been used to study enzyme mechanisms such as those involving ribonucleases. There are no approved medical indications or clinical uses for this compound; it is not marketed or approved by regulatory agencies[1][5][10].

Other names
uridine-2',3'-vanadate1-[(3aS,4R,6S,6aR)-2,2-dihydroxy-6-(hydroxymethyl)-2-oxo-tetrahydrofuro[3,4-d]1,3-dioxa-2-vanadacyclopentan-4-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
02

Targets

RNase A (Pancreatic ribonuclease)

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