Drug intelligence / Profile preview

uridine-5'-diphosphate-2-deoxy-2-fluoro-alpha-D-galactose

Development stage
Unknown
Modality
Small Molecules
01

Overview

Uridine‑5′‑diphosphate‑2‑deoxy‑2‑fluoro‑alpha‑D‑galactose is a synthetic nucleotide sugar analog in which the galactose moiety is modified by fluorination at the 2-position and removal of the corresponding hydroxyl group. It belongs to the class of pyrimidine nucleotide sugars and serves as an experimental substrate for glycosyltransferases in biochemical research. The compound is not approved for therapeutic use but is used primarily as a tool molecule to study glycosylation processes and enzyme specificity. Its mechanism involves acting as a donor substrate in enzymatic glycosylation reactions[1][3][7].

Other names
UDP-2-deoxy-2-fluoro-D-galactoseUDP2-deoxy-2-fluoro-D-galactoseUDP 2-deoxy-2-fluoro-D-galactoseUridine 5'-(trihydrogen diphosphate) P'-(2-deoxy-2-fluoro-alpha-D-galactopyranosyl) ester[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl][(2R,3R,4S,5S,6R)-3-fluoro–4,5-dihydroxy–6-(hydroxymethyl)oxan–2–yl] hydrogen phosphate
02

Targets

B4GALT1 (Beta-1,4-galactosyltransferase 1)

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