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A combination product consisting of a vaginal suppository (vagitory) containing probiotics, typically strains of Lactobacillus such as Lactobacillus acidophilus or Lactobacillus rhamnosus. These products are designed to be inserted into the vagina to help restore or maintain a healthy vaginal microbiome by increasing the population of beneficial bacteria and reducing overgrowth of pathogenic organisms. The primary indications include prevention and adjunctive treatment of bacterial vaginosis, yeast infections, and genitourinary syndrome of menopause. The mechanism involves competitive inhibition against pathogenic microbes and restoration of normal acidic pH via lactic acid production by lactobacilli[1][2][3][7]. Efficacy evidence is mixed; some studies suggest benefit in certain conditions like bacterial vaginosis, but conclusive clinical data are lacking[3][9]. Probiotic vaginal suppositories are generally considered safe for healthy individuals but may cause mild gastrointestinal symptoms or rare allergic reactions; immunocompromised patients should use caution[5][6].
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