valsartan + rosuvastatin

Valsartan + rosuvastatin is a fixed-dose combination of two small molecule drugs used for the concomitant treatment of hypertension and hyperlipidemia. Valsartan is an angiotensin II receptor blocker (ARB) that lowers blood pressure by selectively inhibiting the angiotensin II type 1 (AT1) receptor, thereby blocking vasoconstriction and aldosterone-secreting effects of angiotensin II. Rosuvastatin is a statin that competitively inhibits HMG-CoA reductase, the rate-limiting enzyme in cholesterol biosynthesis, leading to reduced plasma LDL cholesterol levels. The combination provides additive benefits in lowering both blood pressure and LDL cholesterol compared to either drug alone, with studies showing efficacy and safety in patients with coexisting hypertension and dyslipidemia[1][2][3].

Brand names

Rovatitan

Other names

valsartan/rosuvastatinrosuvastatin/valsartan