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VDV-2 + CYD-1,3,4
- Development stage
- Unknown
- Lead developer
- Sanofi Pasteur
- Modality
- Prophylactic Vaccines → Vaccines & Immunotherapeutics
- Administration
- Subcutaneous, Intramuscular
01
Overview
A tetravalent dengue vaccine candidate composed of a blend of **VDV-2 (an attenuated dengue virus serotype 2 vaccine strain)** with **CYD-1, CYD-3, and CYD-4 (chimeric yellow fever-dengue virus strains for serotypes 1, 3, 4)**. This combination is designed to induce a broad immune response against all four dengue virus serotypes by stimulating neutralizing antibodies and cellular immunity. Mechanistically, its main action is as an immunostimulant, aiming to prevent dengue virus infection by eliciting immunity to the four dengue virus types. Developed primarily as a **prophylactic vaccine for dengue fever prevention** in endemic populations[4][1].
- Other names
- Tetravalent blending VDV-2/CYD-1,3,4 Dengue Vaccine
02
Targets
E (Tick-borne encephalitis virus envelope protein)
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