Drug intelligence / Profile preview

VEGF superagonist (human)

Development stage
Preclinical
Lead developer
Trophogen
Modality
Recombinant Proteins and Enzymes
Administration
Intravenous, Parenteral
01

Overview

VEGF superagonist (human) is a recombinant protein analog developed by Trophogen that acts as a high-potency agonist of the vascular endothelial growth factor (VEGF) receptor. While VEGF signaling is typically targeted for inhibition in oncology to suppress angiogenesis, Trophogen's superagonist analogs are engineered to intensely activate these receptors. According to company pipeline information, the drug is in preclinical development for the treatment of thyroid cancer and other malignancies. The therapeutic rationale may involve modulating the tumor microenvironment or enhancing the delivery and uptake of co-administered treatments, leveraging Trophogen's proprietary technology for creating long-acting, high-affinity glycoprotein and growth factor analogs.

Other names
human VEGF superagonistVEGF superagonist analoghuman VEGF superagonist analogs
02

Targets

VEGFR2 (Vascular endothelial growth factor receptor 2)VEGFR-1 (Vascular endothelial growth factor receptor 1)

Beyond the preview

Go deeper on VEGF superagonist (human).

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on VEGF superagonist (human).

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call