vero cell-derived trivalent influenza vaccine (modified)

The **vero cell-derived trivalent influenza vaccine (modified)** is an inactivated influenza vaccine produced using the Vero cell line (derived from African green monkey kidney cells), instead of the traditional embryonated chicken eggs[1][2][3][6][8]. This vaccine contains inactivated viral antigens from three influenza strains: typically two influenza A subtypes (H1N1 and H3N2) and one influenza B lineage (B/Victoria), as recommended for recent influenza seasons[5][7][9]. Vero cell-based production offers advantages including scalability, faster production, and suitability for those with egg allergies[2][3][6][8]. The “modified” formulation refers to changes in composition or production, such as strain selection or cell culture optimization[5][7]. The vaccine works by stimulating the immune system to produce antibodies against the included strains, thereby providing prophylactic protection against influenza infection[3]. Clinically, Vero cell-derived trivalent influenza vaccines have demonstrated efficacy (~78.5% for matched strains) and a favorable safety profile[3].

Brand names

Preflucel

Other names

vero cell-derived trivalent influenza vaccinevero cell trivalent influenza vaccine