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ViaNase + polyclonal immunoglobulin G
- Development stage
- Unknown
- Lead developer
- Kurve Therapeutics
- Modality
- Antibody-Based Therapeutics
- Administration
- Intranasal
01
Overview
**ViaNase + polyclonal immunoglobulin G** is an investigational intranasal, nose-to-brain delivery program that combines Kurve Therapeutics' ViaNase drug-delivery device with a polyclonal immunoglobulin G preparation. Kurve lists the program as a Phase 1/2 human clinical-study combination sponsored by William Rodman Shankle at Hoag Memorial Hospital for neurodegenerative conditions including Alzheimer's disease, Parkinson's disease, Lewy body dementia, chronic traumatic encephalopathy, and multiple system atrophy. The specific antibody source, antigen specificity, molecular targets, and downstream immunological mechanism have not been publicly specified.
- Other names
- ViaNase + polyclonal IgGViaNase / Polyclonal IgG
02
Targets
FCGR2B (Fc gamma receptor IIB)FCGR3B (Fc gamma receptor III)FCGRT (Neonatal crystallizable fragment receptor)
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