Drug intelligence / Profile preview

Villevie prophy paste + Colgate Toothpaste

Development stage
Unknown
Lead developer
Universidade Estadual de Campinas
Modality
Small Molecules
Administration
Topical
01

Overview

Villevie prophy paste + Colgate Toothpaste is a combination oral hygiene regimen evaluated for the management of dentin hypersensitivity, particularly in patients undergoing non-surgical periodontal therapy. This regimen consists of a professional, in-office prophylaxis using Villevie, a fluoride-free polishing paste, followed by the at-home use of a standard Colgate fluoride toothpaste. The treatment approach relies on the mechanical removal of plaque and extrinsic stains by the prophylaxis paste and the subsequent therapeutic action of fluoride from the toothpaste. Fluoride promotes the remineralization of the tooth structure by interacting with hydroxyapatite, which can lead to the partial occlusion of open dentinal tubules and a reduction in the hydrodynamic flow that triggers sensitivity. This specific combination was utilized as a control or comparative arm in clinical trials conducted by the University of Campinas to benchmark the efficacy of newer desensitizing technologies like Pro-Argin.

Brand names
Colgate
Other names
Villevie prophylaxis paste + Colgate toothpasteVillevie + Colgate

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