viscous antibody solution + recombinant human hyaluronidase

This drug is a **combination of a viscous antibody solution** (the specific antibody is not designated here) and **recombinant human hyaluronidase** (typically rHuPH20), an enzyme that transiently degrades hyaluronan in the subcutaneous space. Recombinant human hyaluronidase increases the permeability of subcutaneous tissue, thereby facilitating the subcutaneous delivery, dispersion, and absorption of large and/or viscous therapeutics, such as monoclonal antibody preparations. This component is often used to enable or enhance the subcutaneous administration of drugs that are otherwise difficult to inject or absorb in large volumes. The combination is experimental or in various kit and co-formulation forms for different antibody products[1][3].