Drug intelligence / Profile preview

vitamin b1 + vitamin b6 + vitamin c + vitamin e + mecobalamine

Development stage
Unknown
Lead developer
Merck KGaA
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
Administration
Oral
01

Overview

This is a combination dietary supplement containing five active ingredients: - **Vitamin B1 (thiamine):** Essential for carbohydrate metabolism and nerve function. - **Vitamin B6 (pyridoxine):** Involved in amino acid metabolism, neurotransmitter synthesis, and red blood cell formation[4][5]. - **Vitamin C (ascorbic acid):** An antioxidant that supports immune function, collagen synthesis, and absorption of iron. - **Vitamin E (tocopherol):** A fat-soluble antioxidant protecting cell membranes from oxidative damage. - **Mecobalamine (methylcobalamin):** The neurologically active form of Vitamin B12; essential for DNA synthesis, red blood cell production, and maintenance of the myelin sheath around nerves[3][5]. This combination is used to manage or prevent deficiencies in these vitamins. It may be indicated for neuropathies (including diabetic neuropathy), anemia due to B12 deficiency, general fatigue or weakness related to nutritional deficits, and as supportive therapy in various neurological conditions. The components work synergistically to support cellular metabolism, neurological health, immune defense, and antioxidative protection[5].

02

Targets

MTR (Methionine synthase)PDXK (Pyridoxal kinase)THTR1/THTR2 (Thiamine transporter 1 and 2)TTPA (Alpha-tocopherol transfer protein)Membrane lipid bilayer

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