Drug intelligence / Profile preview

vitamin d + sham exercise

Development stage
Unknown
Modality
Small Molecules
Administration
Oral
01

Overview

This is a combination intervention consisting of oral vitamin D supplementation and a "sham exercise" protocol. Vitamin D is a fat-soluble secosteroid hormone involved in calcium and phosphate homeostasis, bone health, and immune modulation. In clinical trials, the vitamin D regimen typically consists of cholecalciferol (vitamin D3) administered at 10,000 IU three times weekly for 20 weeks[2][3]. The "sham exercise" component refers to an activity designed to mimic the structure or time commitment of an active exercise intervention but without providing its physiological benefits; it serves as a control condition in randomized controlled trials. Sham exercises may include low-intensity balance or toning routines that do not significantly improve aerobic capacity or muscle strength[2][3]. This combination is used as a comparator arm in studies investigating the effects of vitamin D and/or structured exercise on cognitive function, physical performance, or other health outcomes.

02

Targets

VDR (Vitamin D receptor)

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