Drug intelligence / Profile preview

vitamin e + silymarin + carnitine

Development stage
Unknown
Lead developer
BioVie
Modality
Small Molecules
Administration
Oral
01

Overview

Vitamin E + silymarin + carnitine is a combination antioxidant and metabolic supplement, often abbreviated as VSC, studied for the treatment of nonalcoholic fatty liver disease (NAFLD), metabolic syndrome, and type 2 diabetes. The formulation typically comprises 200 IU of vitamin E, 750 mg of silymarin, and 1 gram of L-carnitine. It exerts its therapeutic effects through synergistic antioxidant and anti-inflammatory mechanisms, which help reduce markers of liver inflammation (such as ALT and AST), improve insulin sensitivity, and lower triglyceride levels. Clinical research, including studies associated with Biovil Corporation, has evaluated the efficacy of this three-component combination in improving hepatic function and metabolic parameters.

Other names
VSCvitamin E/silymarin/L-carnitine combination
02

Targets

SLC7A1 (Cationic amino acid transporter 1)TNFA (Tumor necrosis factor alpha (soluble))

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