Drug intelligence / Profile preview

vitex negundo + zingiber officinale

Development stage
Unknown
Lead developer
Enovate Biolife
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Muvz is a proprietary botanical combination of *Vitex negundo* (five-leaf Chinese chaste tree) and *Zingiber officinale* (ginger) developed by Enovate Biolife and marketed by OmniActive Health Technologies. The formula is designed to support joint health and alleviate musculoskeletal discomfort, specifically targeting knee joint pain and low back pain. It utilizes a water extract of *Vitex negundo* leaves and twigs combined with a supercritical CO2 extract of *Zingiber officinale* rhizomes. Muvz exhibits analgesic, antioxidant, and anti-inflammatory properties, with clinical studies demonstrating same-day benefits for exercise-induced knee pain and significant improvements in mobility and flexibility. It is typically administered at a dosage of 200 mg twice daily and is positioned as a natural alternative for managing joint discomfort.

Brand names
Muvz
Other names
Vitex negundo and Zingiber officinale extractNirgundi and Ginger extractfive-leaf Chinese chaste tree and ginger extract
02

Targets

PGHS-1 (Prostaglandin G/H Synthase 1)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)ALOX5 (Arachidonate 5-lipoxygenase)

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