Drug intelligence / Profile preview

VM-1500 + raltegravir

Development stage
Unknown
Lead developer
Viriom
Modality
Small Molecules
Administration
Oral
01

Overview

VM-1500 + raltegravir** is a pharmaceutical combination under investigation for drug-drug interaction and pharmacokinetics, primarily in the context of antiretroviral therapy. VM-1500 is an investigational compound (precise class not specified in public sources). Raltegravir is a first-in-class HIV-1 integrase inhibitor, approved for treatment of HIV infection. Raltegravir blocks the action of HIV integrase, preventing viral DNA from integrating into the host genome. The combination is being explored for possible synergistic or pharmacokinetic compatibility, particularly in healthy volunteers[1][2].

Brand names
Isentress
Other names
VM-1500 + raltegravirVM1500 + raltegravir
02

Targets

Human immunodeficiency virus type 1 reverse transcriptaseIntegrase allosteric pocket (HIV)

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