voriconazole + HSK3486

Voriconazole + HSK3486 is a combination of two pharmaceutical agents. Voriconazole is a triazole antifungal medication used to treat serious fungal infections, including invasive aspergillosis, candidemia, esophageal candidiasis, and other resistant or severe fungal diseases. It works by inhibiting the fungal cytochrome P450 enzyme 14-alpha-lanosterol demethylase, leading to impaired ergosterol synthesis and disruption of the fungal cell membrane[1][3][8]. Voriconazole is primarily developed and marketed under the brand name Vfend by Pfizer[3]. HSK3486 is not described in the provided search results; based on external knowledge, it is an intravenous anesthetic agent (a GABA-A receptor modulator) developed by Haisco Pharmaceutical for procedural sedation and general anesthesia. The combination may be considered for use in clinical settings where both antifungal therapy and anesthesia/sedation are required.

Brand names

Vfend