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Wei's Huoxue Tongluo Recipe
- Development stage
- Unknown
- Lead developer
- Shanghai University of Traditional Chinese Medicine
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Wei's Huoxue Tongluo Recipe is a Traditional Chinese Medicine (TCM) herbal formula primarily developed for the treatment of diabetic peripheral neuropathy (DPN). The recipe is based on the TCM principles of tonifying Qi, activating blood circulation, and dredging the collaterals to address the underlying pathology of 'Qi deficiency and blood stasis' common in chronic diabetic complications. It typically comprises a complex mixture of botanical extracts, including Astragalus membranaceus (Huangqi), Angelica sinensis (Danggui), Ligusticum chuanxiong (Chuanxiong), and Pheretima (Dilong). Clinical research suggests that the formula improves nerve conduction velocity, alleviates symptoms such as numbness and pain, and may exert neuroprotective effects by reducing oxidative stress and improving microcirculation in the peripheral nerves.
- Other names
- Wei's Huoxue Tongluo DecoctionWeishi Huoxue Tongluo FangWei-Shi-Huo-Xue-Tong-Luo
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