Drug intelligence / Profile preview

white kidney bean extract + polyphenol mix extract

Development stage
Unknown
Lead developer
Phase 2
Modality
Small Molecules
Administration
Oral
01

Overview

This is a combination dietary supplement containing **white kidney bean extract** (WKBE) and a **polyphenol mix extract**. **White kidney bean extract** is obtained from Phaseolus vulgaris and is primarily known for its ability to inhibit alpha-amylase, an enzyme responsible for digesting starches, potentially slowing carbohydrate absorption and supporting weight management. **Polyphenol mix extract** generally includes a mixture of plant-derived polyphenols, which are compounds with significant antioxidant and anti-inflammatory properties. When combined, these components are regarded as nutraceuticals aimed at supporting metabolic health, reducing body weight and fat accumulation, improving blood lipid profiles, enhancing glucose metabolism, and positively influencing gut microbiota. The mechanism of action includes alpha-amylase inhibition (for WKBE), antioxidant activity, anti-inflammatory effects, modulation of gut microbiota, and support for metabolic and cardiovascular health. This combination is typically developed and marketed as a dietary/nutraceutical supplement for general metabolic health and weight management, not as a pharmaceutical drug[1][13][8][12].

02

Targets

AMPK (Adenosine monophosphate–activated protein kinase)AMY (Pancreatic alpha-amylase)SIRT1 (NAD-dependent protein deacetylase sirtuin-1)

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