Drug intelligence / Profile preview

white mustard + ginger

Development stage
Preclinical
Modality
Lipid-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Small Molecules
Administration
Topical, Transdermal
01

Overview

A combination of white mustard (Sinapis alba) and ginger (Zingiber officinale) is used in some experimental and traditional formulations, particularly for topical or transdermal applications targeting inflammatory conditions such as arthritis. The combination leverages the anti-inflammatory properties of both ingredients. Ginger contains bioactive compounds like gingerol, 4-hydroxy-3-methoxyphenylacetone, tetrahydrocurcumin, 10-gingerdione, and gingerdiol that may act through multiple anti-inflammatory pathways. White mustard oil is also known for its potential analgesic and counterirritant effects. Together, these ingredients are being investigated for synergistic benefits in pain relief and inflammation reduction when delivered via transdermal patches[1]. There is no evidence this specific combination has been approved as a pharmaceutical drug; it is primarily studied as a novel herbal or dietary supplement approach.

02

Targets

PTGS2 (Prostaglandin-Endoperoxide Synthase 2)RELA (Nuclear Factor Kappa B Subunit p65)PGHS-1 (Prostaglandin G/H Synthase 1)

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