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WJB001 + carboplatin
- Development stage
- Unknown
- Lead developer
- Wigen Biomedicine Technology
- Modality
- Small Molecules
- Administration
- Oral, Intravenous
01
Overview
WJB001 + carboplatin is an investigational combination therapy being studied for the treatment of advanced solid tumors, including high-grade serous ovarian cancer, fallopian tube carcinoma, and peritoneal neoplasms. WJB001 is a small molecule drug developed by Wigen Biomedicine Technology (Shanghai) Co., Ltd. The combination regimen incorporates carboplatin, an organoplatinum alkylating agent that crosslinks DNA, inhibiting cell division and promoting cancer cell death. The goal of combining WJB001 with carboplatin is to enhance antitumor efficacy, with ongoing phase I/II clinical studies exploring safety, tolerability, pharmacokinetics, and preliminary efficacy for various malignancies[2][4][6][8].
- Other names
- WJB001 + carboplatin
02
Targets
N7-G (DNA guanine-N7 adduct)XPO1 (Exportin-1)
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