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wuzi yanzong pill (First Affiliated Hospital of Henan University of Chinese Medicine)
- Development stage
- Unknown
- Lead developer
- First Affiliated Hospital of Henan University of Chinese Medicine
- Administration
- Oral
01
Overview
Wuzi Yanzong pill (WZYP) is a classic Traditional Chinese Medicine (TCM) herbal formula widely utilized for the treatment of male reproductive disorders, particularly oligoasthenospermia (low sperm count and motility). The formula is composed of five botanical seeds: *Cuscutae Semen* (Tu Si Zi), *Lycii Fructus* (Gou Qi Zi), *Rubi Fructus* (Fu Pen Zi), *Schisandrae Chinensis Fructus* (Wu Wei Zi), and *Plantaginis Semen* (Che Qian Zi). Traditionally described as a 'kidney-tonifying' and 'spermatogenic' remedy, modern research indicates that WZYP improves sperm quality by modulating the expression of specific microRNAs (miRNAs) involved in spermatogenesis, reducing oxidative stress, and inhibiting apoptosis in testicular germ cells. It is a standard treatment in China for male infertility and is often studied for its protective effects on the blood-testis barrier and mitochondrial function in sperm.
- Brand names
- Wuzi Yanzong WanWuzi Yanzong Pill
- Other names
- Five Seeds for Passing on the GenerationsFive Seeds Teapills
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