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Xi'an Jiaotong Univ. EGFRDel19/T790M/C797S TK compound Os30
- Lead developer
- Xi'an Jiaotong University
01
Overview
Xi'an Jiaotong Univ. EGFRDel19/T790M/C797S TK compound Os30: sourced facts only. name: "Consequently, compound Os30 exhibited potent inhibitory activities against both EGFRDel19/T790M/C797S TK and EGFRL858R/T790M/C797S TK with IC50 values of 18 nM and 113 nM, respectively."; target: "Consequently, compound Os30 exhibited potent inhibitory activities against both EGFRDel19/T790M/C797S TK and EGFRL858R/T790M/C797S TK with IC50 values of 18 nM and 113 nM, respectively."; developer: "Department of Medicinal Chemistry, School of Pharmacy, Xi'an Jiaotong University, Xi'an, Shaanxi, 710061, PR China."; stage: "More importantly, Os30 showed potent antitumor efficacy in the KC-0116 cells xenograft nude mice tumor model with the tumor growth inhibitory rate of 77.6% at a dosage of 40 mg/kg."
02
Targets
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