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Xiao'er Biantong Granule
- Development stage
- Phase 1
- Lead developer
- First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
- Administration
- Oral
01
Overview
Xiao'er Biantong Granule (also known as Xiao'er Tongbian Granule) is a traditional Chinese medicine (TCM) granule developed for the treatment of pediatric functional constipation, particularly for cases with traditional Chinese medicine dyspepsia syndrome (food accumulation syndrome). Formulated from a clinical experience prescription of Dr. Chen Yonghui, the herbal mixture contains active ingredients such as Atractylodes macrocephala (白术), Aurantii Fructus (枳壳), Magnoliae Officinalis Cortex (厚朴), and Raphani Semen (莱菔子) to invigorate the spleen, regulate qi, and promote digestion and defecation. Originally developed as Xiao'er Biantong Granule, it was approved by the National Medical Products Administration (NMPA) of China in August 2026 under the name Xiao'er Tongbian Granule as a Class 1.1 TCM innovative drug.
- Other names
- XEBT granulesXiao'er Biantong GranulesXiao'er Tongbian GranuleXiao'er Tongbian Granules小儿便通颗粒小儿通便颗粒
02
Targets
AQP3 (Aquaporin-3 channel protein)MOR (Mu opioid receptor)
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