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xiaozhong zhitong plaster + traditional chinese medicine powder
- Development stage
- Preclinical
- Lead developer
- Affiliated Hospital of Shandong University of Traditional Chinese Medicine
- Modality
- Small Molecules
- Administration
- Topical
01
Overview
Xiaozhong Zhitong plaster + traditional chinese medicine powder is a combination therapy developed by the Affiliated Hospital of Shandong University of Traditional Chinese Medicine (TCM) for the treatment of postherpetic neuralgia (PHN). The treatment involves the topical application of the Xiaozhong Zhitong plaster, a traditional formulation known for its ability to promote blood circulation, remove blood stasis, and reduce swelling, in conjunction with a specific TCM powder. This combination is designed to target the chronic neuropathic pain that persists after a herpes zoster (shingles) infection. The therapy works by clearing heat, detoxifying the affected area, and unblocking the collaterals (meridians) to alleviate the intense burning or stabbing pain characteristic of PHN. It is typically used as an external application directly on the site of the neuralgia.
- Other names
- Xiaozhong Zhitong plaster plus TCM powderXiaozhong Zhitong Gao plus traditional Chinese medicine powder
02
Targets
IL1B (Interleukin-1 beta)PKA (Cyclic amp-dependent protein kinase)PRKCG (Protein kinase C gamma)PAR2 (Protease-activated receptor 2)TRPV1 (Transient receptor potential cation channel subfamily V member 1)TNFA (Tumor necrosis factor alpha (soluble))
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