Drug intelligence / Profile preview

xingnaojing + shuxuetong

Development stage
Unknown
Modality
Peptides, Small Molecules, Recombinant Proteins and Enzymes
Administration
Intravenous
01

Overview

Xingnaojing + Shuxuetong is a combination therapy consisting of Xingnaojing injection and Shuxuetong injection, both of which are traditional Chinese medicine (TCM) injectable formulations. Xingnaojing is derived from the Angong Niuhuang pill and contains botanical ingredients such as Dryobalanops aromatica (borneol), Curcuma aromatica (curcuma root), Gardenia jasminoides (gardenia fruit), and Moschus species (musk). It is used for its purported effects in clearing heat, detoxifying, promoting blood circulation, and restoring consciousness. Shuxuetong is typically prepared from leech extract or other TCM components aimed at promoting blood circulation and removing blood stasis. The combination has been studied primarily for acute cerebrovascular diseases such as cerebral infarction (ischemic stroke) and intracerebral hemorrhage. Clinical studies suggest that this combination may improve neurological outcomes, reduce mortality rates, lower neurological deficit scores, and does not significantly increase adverse drug reactions compared to standard regimens or monotherapy with either agent[3][1]. The mechanism of action involves multiple pathways including anti-inflammatory effects, neuroprotection, improvement of microcirculation, reduction of cerebral edema, promotion of hematoma absorption in hemorrhagic stroke patients[2][3].

Other names
xingnaojing injection + shuxuetong injection
02

Targets

F2 (Thrombin)GLP1R (GLP-1R)

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