Drug intelligence / Profile preview

zinc citrate trihydrate + zinc sulphate heptahydrate

Development stage
Unknown
Modality
Small Molecules
Administration
Oral
01

Overview

This is a **combination mineral supplement** containing two different water-soluble zinc salts: **zinc citrate trihydrate** and **zinc sulphate heptahydrate**. Both forms are approved and widely used as sources of zinc to **prevent or treat zinc deficiency** and as adjuncts to oral rehydration therapy (ORT) for the management of diarrhea in children[1][2][3][4]. Zinc plays a critical role in numerous biological functions, including enzyme activity, immune function, protein synthesis, wound healing, and DNA synthesis. **Zinc citrate** is noted for its high absorption and improved sensory characteristics in syrups, while **zinc sulphate** (especially as heptahydrate) is the most commonly used, economically preferred form in both tablets and solutions[1][3]. There is no clinically significant difference in efficacy or safety between these salts when used as supplements[1][3]. The mechanism of action is broad, stemming from normalizing or augmenting zinc-dependent enzymatic and cellular processes[2][4].

Other names
zinc citrate trihydratezinc sulphate heptahydratezinc citratezinc sulfate heptahydrate

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