Drug intelligence / Profile preview

zinc oxide + propolis

Development stage
Preclinical
Lead developer
National Eye Institute
Modality
Nanoparticles → Drug Delivery Systems, Small Molecules
Administration
Topical, Oral
01

Overview

Zinc oxide + propolis is a combination product typically formulated as a nanocomposite or nanoparticle system that merges the antimicrobial and antioxidant properties of zinc oxide (ZnO) with the bioactive compounds found in propolis. This combination has been developed to address challenges such as antibiotic resistance and oxidative stress. The mechanism involves both direct antibacterial action—where ZnO nanoparticles disrupt bacterial cell membranes—and synergistic effects from propolis, which contains flavonoids and phenolic acids that further enhance antimicrobial efficacy. Studies have shown this composite to be effective against Gram-positive and Gram-negative bacteria, including multidrug-resistant strains like Pseudomonas aeruginosa and Escherichia coli[1][5]. Additionally, the combination exhibits significant antioxidant activity and enzyme inhibition relevant for antidiabetic effects[5]. The formulation is often produced via green synthesis methods using plant-based extracts for safety and environmental compatibility[1][2].

Other names
ZnO-propolis nanocompositeZnO-P NCsPro-ZnO NPs
02

Targets

Sucrase-IsomaltaseAMY (Pancreatic alpha-amylase)

Beyond the preview

Go deeper on zinc oxide + propolis.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on zinc oxide + propolis.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call