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zovaglutide + rosuvastatin + digoxin
- Development stage
- Unknown
- Lead developer
- QL Biopharm
- Modality
- Peptides, Small Molecules
- Administration
- Subcutaneous, Oral
01
Overview
ZT002 + rosuvastatin + digoxin is a drug combination evaluated in a Phase 1 drug-drug interaction (DDI) study. ZT002 (zovaglutide) is an ultra long-acting glucagon-like peptide-1 receptor agonist (GLP-1 RA) developed by Beijing QL Biopharmaceutical for the treatment of obesity and type 2 diabetes. Rosuvastatin is an HMG-CoA reductase inhibitor (statin) used for lipid management, and digoxin is a cardiac glycoside used for heart failure and arrhythmias. The combination is specifically studied to determine if the administration of ZT002 affects the pharmacokinetics of rosuvastatin and digoxin, which are common co-medications in the target patient population.
- Other names
- zovaglutide + rosuvastatin + digoxin
02
Targets
HMGCR (3-hydroxy-3-methylglutaryl-coenzyme A reductase)GLP1R (GLP-1R)
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