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Target intelligence / Profile preview
3,4-Methylenedioxy-N-methylamphetamine (MDMA)
- Target
- MDMA
- Molecular classification
- Empathogen-entactogen, Stimulant, Psychedelic
01
Overview
3,4-Methylenedioxy-N-methylamphetamine (MDMA) is a psychoactive drug primarily known for its empathogenic effects. It acts by increasing the activity of serotonin, dopamine, and norepinephrine in the brain, leading to altered mood, perception, and cognition. While recreationally used, it has also been studied for therapeutic applications, particularly in the treatment of PTSD and social anxiety.
- Other names
- EcstasyMollyAdamXTCN-methyl-3,4-methylenedioxyamphetamineMethylenedioxymethamphetamine(RS)-3,4-(Methylenedioxy)methamphetamine
02
Mechanism of action
MDMA acts as a substrate and inhibitor of monoamine transporters (SERT, DAT, NET), leading to increased levels of serotonin, dopamine, and norepinephrine in the synapse.
03
Biological functions
Monoamine neurotransmitter releaseInhibition of monoamine reuptake
04
Disease associations
Post-traumatic stress disorder (PTSD)Social anxiety associated with autism spectrum disorder
05
Safety considerations
NeurotoxicityHyperthermiaSerotonin syndromeHyponatremiaCardiovascular complicationsPsychiatric effects
06
Interacting drugs
Serotonin releasers
2 more in the full profile.
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