39S ribosomal protein L22, mitochondrial (MRPL22)

39S ribosomal protein L22, mitochondrial (MRPL22) is a structural protein component of the large 39S subunit of the mitochondrial ribosome in humans, encoded by the nuclear gene MRPL22[1][2][6]. It is essential for protein synthesis within mitochondria, functioning in mitochondrial translation[1][2][3]. Mammalian mitochondrial ribosomal proteins, including MRPL22, differ significantly in sequence among species and are largely responsible for assembling proteins encoded by mitochondrial DNA. MRPL22 does not serve as a therapeutic target, and no specific disease associations, interacting drugs, or biomarker roles are documented in current databases[1][2][6].

Other names

Large ribosomal subunit protein uL22mMRPL22MRPL25RPML25HSPC158L22mtMRP-L22L25mtMRP-L25uL22m39S ribosomal protein L25, mitochondrial