7SL RNA, cytoplasmic 761, pseudogene (RN7SL761P)

RN7SL761P is a pseudogene derived from the 7SL RNA gene family, specifically classified as "RNA, 7SL, cytoplasmic 761, pseudogene." The 7SL RNA gene encodes the RNA component of the signal recognition particle (SRP), which plays a vital role in targeting secretory proteins to the endoplasmic reticulum membrane[3][5]. In contrast, RN7SL761P is a non-functional, non-coding genomic DNA sequence that resembles the functional 7SL RNA gene but is not transcribed into active RNA[1]. The majority of 7SL pseudogenes, including RN7SL761P, are believed to originate from the genomic integration of reverse-transcribed RNAs and typically lack biological activity[1]. RN7SL761P is not a protein-coding gene and does not produce a functional RNA or protein product[1]. There is no evidence suggesting that RN7SL761P functions as a receptor, enzyme, transport protein, or other therapeutic target. It is not implicated in pharmacological interactions or disease processes[1]. While functional 7SL RNA participates in SRP-mediated targeting of proteins, RN7SL761P is a truncated, non-functional copy and lacks biological function[1][5]. Other similarly named pseudogenes such as RN7SL676P and RN7SL361P exist; these are also non-functional genomic elements[2][4]. The designation as a pseudogene means RN7SL761P is not a standard drug target and holds no known clinical or molecular function relevant to disease mechanisms, drug interactions, or biomarker utility[1][3][5]. The entry is marked is_incorrect: true because requesting therapeutic target data for a pseudogene that is not biologically active is conceptually incorrect per field conventions. If structured information on a functional SRP RNA (7SL RNA) is required, that would be a distinct entry with functional characteristics, biological roles, and potential clinical significance[3][5].

Other names

RN7SL761PRNA, 7SL, cytoplasmic 761, pseudogene