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The adrenergic system is a regulatory component of the autonomic nervous system that uses the neurotransmitters epinephrine (adrenaline) and norepinephrine (noradrenaline) to mediate neural and endocrine functions throughout the body. This system plays a central role in controlling cardiovascular, respiratory, metabolic, and other physiological processes by acting through specific cell surface receptors known as adrenergic receptors. These receptors are primarily divided into two main classes—alpha (α) and beta (β)—with further subtypes within each class: Alpha-1 (α1), Alpha-2 (α2), Beta-1 (β1), Beta-2 (β2), and Beta-3 (β3). Each subtype has distinct tissue distributions and physiological roles.
Agonism or antagonism of adrenergic receptors, modulating downstream signaling pathways.
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