Amino acid metabolism enzyme ()

Amino acid metabolism enzyme Overview

Amino acid metabolism enzymes are a **broad class** of proteins that catalyze the biochemical reactions involved in both the synthesis (anabolism) and breakdown (catabolism) of amino acids. These enzymes include aminotransferases, dehydrogenases, decarboxylases, among others. They play essential roles in maintaining cellular homeostasis by regulating protein synthesis, energy production through conversion to TCA cycle intermediates or ketone bodies, nitrogen disposal via urea formation, and biosynthesis of other critical molecules such as neurotransmitters and nucleotides. Many key steps occur within mitochondria and require cofactors like pyridoxal phosphate (vitamin B6), tetrahydrofolate (vitamin B9), cobalamin (vitamin B12), thiamine pyrophosphate (vitamin B1), coenzyme A (vitamin B5), NAD+/NADP+ (niacin/B3), FAD/FMN (riboflavin/B2)[2][5]. Dysfunction in these enzymes is implicated in a range of diseases including cancer and inherited metabolic disorders. However, "amino acid metabolism enzyme" is not a single molecular entity but rather refers to an entire functional category encompassing many distinct proteins with diverse structures and functions[1][2]. Notes on correctness ("is_incorrect"): The term "Amino acid metabolism enzymes" is **not a single molecular target** but instead refers to an entire group/family comprising many different specific proteins/enzymes. For structured data purposes or drug discovery efforts it would be necessary to specify which particular enzyme(s) are meant—such as "Glutamate dehydrogenase," "Aspartate aminotransferase," etc.—rather than using this umbrella term[1][2].

Mechanism of Action

Biological Functions

Safety Considerations