Molecular Classification
Enzyme, Exopeptidase, Metalloaminopeptidase, Cysteine aminopeptidase
Disease Roles
CancerPain sensationBlood pressure regulation

Aminopeptidase Overview

Aminopeptidases are a class of exopeptidase enzymes that catalyze the cleavage of amino acids from the N-terminus of proteins or peptides. They are widely distributed and play essential roles in protein and peptide metabolism, including digestion and the regulation of bioactive peptides. Some aminopeptidases are implicated in diseases such as cancer, making them potential drug targets.

Mechanism of Action

Hydrolyzes the terminal peptide bond at the N-terminal end of proteins and peptides, releasing single amino acid residues.

Biological Functions

Protein metabolism
Peptide metabolism
Digestion
Regulation of bioactive peptides
Protein turnover

Disease Associations

Cancer
Pain sensation
Blood pressure regulation
Tumor progression
Metastasis

Safety Considerations

No safety concerns listed

Interacting Drugs

Bestatin