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Target intelligence / Profile preview
Angiotensin I converting enzyme 3, pseudogene (ACE3P)
- Target
- ACE3P
- Molecular classification
- Other (Pseudogene; non-coding)
01
Overview
Angiotensin I converting enzyme 3, pseudogene (ACE3P) is classified as a **pseudogene** in the human genome, with no demonstrated protein-coding capacity or functional enzyme activity[3]. Despite nomenclature similarity to angiotensin-converting enzyme (ACE)—a well-characterized target involved in blood pressure regulation[1][2][4]—ACE3P is not an active enzyme and is not a recognized therapeutic target. Its predicted location in the acrosomal vesicle (from gene annotation) does not imply protein expression or biological activity[3]. Clinical drugs and research focus on the functional ACE isoforms but not on ACE3P. There are no associated drugs, mechanisms of action, biomarkers, or disease roles for ACE3P. The target name is therefore **incorrect as a drug or therapeutic target**; it should not be listed as an active or actionable molecule in pharmacology or drug discovery.
- Other names
- Angiotensin I converting enzyme 3, pseudogenePeptidyl-dipeptidase A, pseudogeneACE3Angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 pseudogeneAngiotensin I converting enzyme (peptidyl-dipeptidase A) 3, pseudogeneAngiotensin converting enzyme-3 pseudogeneACE3P
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